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Ashley Bennett

Ashley Bennett

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Postdoctoral Scholar

Duke Human Vaccine Institute, Duke University

Technologies

My Portfolio Highlights

My New Course

Introduction to Python

If the truth shall kill them, let them die

My Work

Take a look at my latest work.

project

Predictive Modeling for Agriculture

Python
course

Supervised Learning with scikit-learn

Python
course

Intermediate Data Visualization with Seaborn

Python

My Certifications

These are the industry credentials that I’ve earned.

Data Literacy

Data Literacy

DataCamp Course Completion

Take a look at all the courses I’ve completed on DataCamp.

My Work Experience

Where I've interned and worked during my career.

The Duke Human Vaccine Institute | Jan 2021 - Present

Postdoctoral Researcher

Project 1: Conformational transitions in HIV-1 Env. · Design and implement molecular dynamics protocols and simulations with Amber to integrate with experimental work for various projects. · End-to-end design and implementation of analysis and visualization programs in Python, Tcl, and bash languages to assist with and automate data analysis. · Determine projection paths for adaptive sampling. · Parameterize small molecule compounds for molecular dynamics. · Prepare manuscripts for publication. · Prepare DNA and protein of HIV-1 Env mutants. · Perform BLI, SPR, and cryo-EM experiments. · Developed workflow for time-resolved, temperature SAXS of viral fusion proteins. · Developed analysis software implemented in Python to analyze time-resolved SAXS data.
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Proton Therapeutics, LLC | Mar 2020 - Present

Scientific Director

Managed a start up business by successfully registering with proper federal institutions to be eligible for small business grants from the National Institutes of Health. Provide scientific expertise during grant writing and experimental work.

Virginia Commonwealth University School of Medicine | Sep 2019 - Jan 2021

Laboratory Technician

Main Project: Structure of electrostatic networks and mechanisms of pH sensing in Hv1. Designed and implemented molecular dynamics protocols and simulations in NAMD to integrate with experimental work. Implemented analysis and visualization programs in Python, Tcl, and Bash languages to assist with and automate data analysis. Performed homology modelling using the Python package Modeller to build homology models of ion channels Hv1 and TRPV2. Built and maintained and Linux GPU workstation to run molecular dynamics simulations, visualizations, and analysis. Developed a system for keeping an electronic lab notebook and managing massive amounts of data. Designed and conducted electrophysiological experiments to test hypotheses developed by computational work. Performed various molecular biology and cell culture techniques to maintain cell lines and generate cDNA of target proteins for experiments. Presented research in various seminars, poster sessions, and Biophysical Society Meetings.

Virginia Commonwealth University | Jul 2014 - Sep 2019

Graduate Student Researcher

Main Project: Structure of electrostatic networks and mechanisms of pH sensing in Hv1. Designed and implemented molecular dynamics protocols and simulations in NAMD to integrate with experimental work. Implemented analysis and visualization programs in Python, Tcl, and Bash languages to assist with and automate data analysis. Performed homology modelling using the Python package Modeller to build homology models of ion channels Hv1 and TRPV2. Built and maintained and Linux GPU workstation to run molecular dynamics simulations, visualizations, and analysis. Developed a system for keeping an electronic lab notebook and managing massive amounts of data. Designed and conducted electrophysiological experiments to test hypotheses developed by computational work. Performed various molecular biology and cell culture techniques to maintain cell lines and generate cDNA of target proteins for experiments. Presented research in various seminars, poster sessions, and Biophysical Society Meetings.

University of North Carolina at Wilmington | Jan 2013 - May 2014

Student Researcher

Worked in the laboratory of Dr. Hee-Seung Lee in the Department of Chemistry and Biochemistry performing computational research. Focus of research was placed on using in silico approaches to investigate antimicrobial peptide interactions with lipid membranes.

Intracellular Regulation Group, NIEHS, NIH | May 2012 - Aug 2012

Summer Research Intern

Determining the signaling cascade involved in glucocorticoid induced changes in ABC transporter activity at the blood-brain barrier using confocal microscopy and molecular techniques.

Carolina at Wilmington | Aug 2011 - Dec 2011

Student Researcher

The lab of Dr. Arthur Frampton focuses on elucidating the signaling pathways and cell factors that are critical for a productive equine herpes virus infection to occur using multiple molecular techniques.

Intracellular Regulation Group, NIEHS, NIH | May 2011 - Aug 2011

Summer Research Intern

Determining the signaling cascade involved in dioxin induced changes in ABC transporter activity at the blood-brain barrier using confocal microscopy and molecular techniques.

Department of Biology and Marine Biology, University of North

Undergraduate Student

N/A

My Education

Take a look at my formal education

Doctor of Philosophy (Ph.D.), Ion Channel BiophysicsVirginia Commonwealth University School of Medicine | 2019
Bachelor’s Degree, Biology, GeneralUniversity of North Carolina at Wilmington | 2014
Bachelor’s Degree, ChemistryUniversity of North Carolina at Wilmington | 2014
High School Athens Drive High School | 2008

About Me

Ashley Bennett

I am a biophysicist specializing in time-resolved SAXS, molecular dynamics, homology modeling, and various biophysical experimental methods exploring conformational transitions and structure-based mechanisms in ion channels and fusion proteins.

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