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Gerald Bothe

Gerald Bothe

Data Analyst/Data Curator


My Portfolio Highlights

My New Course

Introduction to Python

Quantitative architect, designing solutions with numbers as building blocks.

My Work

Take a look at my latest work.


Data Manipulation with dplyr


Introduction to the Tidyverse


Introduction to Python

DataCamp Course Completion

Take a look at all the courses I’ve completed on DataCamp.

My Work Experience

Where I've interned and worked during my career.

La Jolla Institute for Immunology | Jan 2022 - Jan 2023

Scientific Data Curator

Curation of immunology data for the Immune Epitope Database (IEDB.org)

Rancho Biosciences | Jan 2015 - Jan 2022

Scientific Data Curator

Unifying metadata for molecular biology experiments and making them accessible to the company's scientific community. Next generation sequencing (NGS), microarray, PCR, ELISA and other technologies Oncology and immunology disease areas Genetic variant curation Scientific data curation of genetics, molecular biology and microbiology data Windows and Linux systems ISAcreator non-relational database tool, use of ontologies for data harmonization Data classification and database structure design for microbiology and molecular biology Data wrangling using R tidyverse
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Wadsworth Center | Jan 2013 - Jan 2016

Visiting Scientist

- Phenotyping of mouse models of Autism, e. g. Btbr - Identification of Autism quantitative trait loci (QTL) - R Statistical analysis; R/qtl for QTL analysis

University of Chicago | Jan 2014 - Jan 2015

Research Manager/Scientific Coordinator

• Established a new multi-center research project working for Principal Investigator • Management of pilot project grant submissions • Creation and maintenance of Standard Operating Procedures (SOPs) for sample collection • Created project website, website maintenance • Organized the first project conference with 30 participants • Planned the center database in collaboration with the center’s computer scientist • Familiar with Genotyping by Sequencing (GBS) technology

Taconic | Jan 1999 - Jan 2013

Senior Scientist

- Developed assays, processes, and automation for rodent genotyping - Genetic Background analysis using Illumina bead arays - Development of SNP panels for genetic analysis using NGS data - Developed DNA and RNA assays for the detection of bacteria and viruses of veterinary importance - Research on standardized behavior testing of inbred, mutant and knock-out mouse strains - Identified, researched and managed the introduction of new technologies such as pyrosequencing - Phenotyping of transgenic mouse models, e.g. APP-SWE Alzheimer model - Identified Autism quantitative trait loci (QTL) in collaboration with academic researchers - R statistical analysis, JMP, R/qtl for QTL analysis - Bioinformatics - CLUSTALL, BLAST, Vector NTI, CLC Gene Workbench, Illumina Genome Studio, GALAXY, Perl - Organized contract research projects for clients, preparing statements of work (SOW) and IACUC submissions - Supporting business development in cooperation with product management - Project management of R&D effort in cross-functional teams and R&D committee

Lexicon Genetics (now Lexicon Pharmaceuticals) | Jan 1998 - Jan 1999


- Used high-throughput gene targeting technology to produce knock-outs, knock-ins and conditional mutations - Utilized both cloning and yeast recombineering approaches for gene targeting - Participated in the production of over ten targeted lines in a one-year period - Participated in evaluation of drug target candidates

Skirball Institute, New York University Medical Center | Jan 1995 - Jan 1998

Postdoctoral Research Scientist

- Responsible for establishing the Cre/loxP tissue-specific knockout mouse technology. - Designed and performed experiments for generating gene-targeted mice. - Analyzed Cre activity in diverse tissues and contributed to investigating the role of erbB receptors and nrg ligands in neuromuscular synapse formation using the Cre mice.

Columbia University | Jan 1993 - Jan 1995

Postdoctoral Research Fellow


My Education

Take a look at my formal education

Barnett International
University of Washington
Cornell University School of Industrial and Labor Relations
University of Konstanz
University of Hamburg

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