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Helen Brabham

Research Team Lead

2Blades

Technologies

My Portfolio Highlights

My New Course

Introduction to Python

Quantitative storyteller, captivating audiences with tales of data analysis.

My Work

Take a look at my latest work.

course

Data Manipulation with pandas

course

Introduction to Python

course

Intermediate Python

DataCamp Course Completion

Take a look at all the courses I’ve completed on DataCamp.

My Work Experience

Where I've interned and worked during my career.

2Blades | Jun 2020 - Present

Research Development Lead

- Leading global program execution for the non-profit 2Blades NLRseek research platform, delivering new validated plant disease resistance genes. - Collaborating with academia and industry to develop functional gene prediction and protein-protein interactions for in planta validation of resistance. - Presented at 5 international conferences including keynote presentation at the International Congress Of Plant Pathology 2023 to ~2,500 attendees.
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ResNet | Mar 2018 - May 2023

ResNet representative for TSL

ResNet is a grassroots contact and information network promoting gender equality and fairness at the UEA, The John Innes Centre, The Quadram Institute, The Earlham Institute and The Sainsbury Laboratory. ResNet aims to provide an interesting calendar of events that promotes career development; provides inspiration, information and support; raises awareness of the importance of equality in the workplace and gets people talking to each other.

The Sainsbury Laboratory | Oct 2019 - Jun 2020

Postdoctoral Research Scientist

- Genetic mapping and validation of new plant disease resistance genes in barley. Barley MLA3 recognizes the host- specificity effector Pwl2 from Magnaporthe oryzae - Managed global research collaborations in USA, Mexico, Europe, and Japan. - Data analysis and scientific computing using HPC, Bash, Python, conda environments, and R. - Supervised Masters and PhD students in diverse experiments for biological insight.

The Sainsbury Laboratory | Sep 2015 - Oct 2019

PHD Research Scientist

- Designed and implemented diverse experiments and bioinformatics for genetic mapping, characterisation, and validation of plant disease resistance genes and plant pathogen recognition. - Data analysis and scientific computing using HPC, Bash, Python, conda environments, and R. - Supervised Masters and undergraduate summer students in project design and day-to-day management. - Designed and delivered public outreach activities including presentations at the Norwich Science Festival, Pint of Science, and the Women of the Future Conference. - Technical experience with: RNA-seq and NGS analysis, genetic mapping (bi-parental populations, QTL mapping, fine-mapping), phenotyping of fungal pathogens, cloning and construct development (Gibson Assembly, USER cloning, Golden Gate), CRISPR/Cas-9, transgenic plants, fungal transformation, fluorescence microscopy, and DNA and RNA-extraction.

Code First: Girls | Jan 2019 - Mar 2019

Course student

- Completion of the level 1 beginners course in web development. - Front-end programming including HTML, CSS, JavaScript, jQuery, Git, GitHub collaboration. Code First: Girls is a multi-award winning social enterprise, focusing on increasing the diversity in tech through free training courses, providing a community and network of professional support, and corporate activities. https://www.codefirstgirls.org.uk/

Japan Society for the Promotion of Science | Jun 2018 - Aug 2018

JSPS Summer Program

N/A

University of Bristol | Sep 2014 - Feb 2015

Third Year Practical Project: "The Effect of Viral Infection on Drought Tolerance in Plants"

- Worked under the supervision of Dr Rose Murray in the laboratory of Prof. Gary Foster at the University of Bristol. - Tested the the hypothesis of improved drought tolerance under TMV infection using 4 plant species. - ABA-induced stomatal closure under viral infection was investigated using the ost-1 mutant of Arabidopsis thaliana infected with Turnip vein clearing virus (TVCV). - Viral infection was shown to increase drought tolerance through increased water percentage of the plant, reduction of drought symptoms as a lower percentage of dead leaves, and an increased resistance to the onset of drought symptoms. - The improvement of drought tolerance was not virus specific as both TMV and TVCV induced the response.

University of Bristol | Jul 2014 - Aug 2014

Summer Placement

I worked with Professor Keith Edwards looking into the potential for using genetic techniques such as KASP genotyping to distinguish between nullisomic and monosomic wheat.

Cardiff University | Jul 2013 - Jul 2013

Laboratory Assistant

Laboratory Work with the DURESS project in Cardiff University with Dr Hugh Feeley. During this time I also carried out mink dissections with the Cardiff Otter Project.

Operation Wallacea | Jul 2013 - Jul 2013

Research Assistant

Carried out habitat and game assessments in Balule nature reserve, South Africa. We worked as a team creating transects to measure habitat type and density, carried out bird point and game counts. Also gained my PADI open water diving qualification in Sodwana Bay during this time.

Cardiff University | Jun 2011 - Jul 2011

Nuffield Project Student

Worked with Dr Kelly BéruBé and carried out a Nuffield Science Project entitled "Bio Reactivity of Volcanic Ash: are Health Effects Erupting?" and obtained a Gold CREST award for the project.

My Education

Take a look at my formal education

Executive Master of Business Administration   · (September 2023 - OctoberUniversity of East Anglia | 2025
Postgraduate Certificate, Higher Education PracticeUniversity of East Anglia | 2020
Doctor of Philosophy (Ph.D.) University of East Anglia | 2019
Bachelor’s Degree, Biology, GeneralUniversity of Bristol | 2015
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